You have probably performed a sandwich assay before, even if you didn't know it. Sandwich assays are the molecular sensing ...

A double-strand DNA break (DSB) occurs or arises when both strands of the DNA duplex are severed, often as the result of ionizing radiation. They are particularly deleterious as the DNA ends can ...

Scientists filmed a tiny protein complex changing shape and gripping DNA, revealing how it captures and holds different DNA ...

High-speed atomic force microscopy has revealed how the Smc5/6 protein complex changes shape, captures DNA and tethers ...

Researchers have developed a novel sequencing technique called Methyltransferase-Assisted Single Duplex sequencing, or ...

High-speed nanoscale imaging reveals how a protein structure changes shape to capture and pack DNA more tightly.

Watson and Crick's discovery of DNA structure in 1953 revealed a possible mechanism for DNA replication. So why didn't ...

At-home COVID-19 tests work because they use a clever molecular trick known as a sandwich assay. One molecule grabs the virus, another molecule grabs the same virus from a different side, and together ...

Cells are very particular about the proper locations of their contents. For example, DNA is packaged in the nucleus in a ...

King’s College London neuroscientists report that KCL-286, an experimental pill first developed for spinal cord injuries, ...